Title
Pharmacophores and Pharmacophore Searches (Methods and Principles in Medicinal Chemistry, Vol. 32),Used
Delivery time: 8-12 business days (International)
This handbook is the first to address the practical aspects of this novel method. It provides a complete overview of the field and progresses from general considerations to real life scenarios in drug discovery research.Starting with an introductory historical overview, the authors move on to discuss ligandbased approaches, including 3D pharmacophores and 4D QSAR, as well as the concept and application of pseudoreceptors. The next section on structurebased approaches includes pharmcophores from ligandprotein complexes, FLIP and 3D proteinligand binding interactions. The whole is rounded off with a complete section devoted to applications and examples, including modeling of ADME properties.With its critical evaluation of pharmacophorebased strategies, this book represents a valuable aid for project leaders and decisionmakers in the pharmaceutical industry, as well as pharmacologists, and medicinal and chemists.
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This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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