Title
Polimorfismo Fok I del VDR y Recambio seo en Pacientes con Ortodoncia: Polimorfismo Fok I del Receptor de Vitamina D y Recambi,Used
Delivery time: 8-12 business days (International)
Cada da son ms los adultos que se someten a tratamiento ortodncico. Durante el tratamiento ortodncico existe susceptibilidad de prdida sea a nivel marginal, que comprometer la longevidad de la pieza dentaria. Por esto, debemos considerar los principios biolgicos que fundamentan el movimiento dentario. La vitamina D y la PTH participan en la regulacin del metabolismo mineral seo. Las variaciones en la sntesis de la PTH y su secrecin se deben a cambios en la expresin gnica de la PTH, regulada por el 1,25dihidroxivitamina D, metabolito activo de la vitamina D, y su receptor nuclear (VDR) junto con el nivel srico de calcio y fsforo. Un estudio de la secuencia de nucletidos del ADN genmico del VDR muestra la existencia de 2 codones de comienzo en la transcripcin (ATG). Se detect un polimorfismo T/C en el 1 codn de inicio usando el enzima Fok I.Esta mutacin origina una protena 3 aminocidos ms corta, de modo que se ven alteradas sus funciones, como la regulacin de la expresin de genes implicados en la remodelacin sea y se ha asociado esta mutacin, en algunas poblaciones, con una mayor densidad mineral sea y una menor predisposicin a sufrir osteoporosis.
By changing our most important processes and
products, we have already made a big leap forward. This ranges from the
increased use of more sustainable fibers to the use of more
environmentally friendly printing processes to the development of
efficient waste management in our value chain.
⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.