Protein Crystallography: A Concise Guide,New

Protein Crystallography: A Concise Guide,New

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The proteome remains a mysterious realm. Researchers have determined the structures of only a small fraction of the proteins encoded by the human genome. Crystallography continues to be the primary method used to determine the structures of the remaining unknown proteins. This imaging technique uses the diffraction of Xrays to determine a proteins threedimensional molecular structure.Drawing on years of research and teaching experience, Eaton E. Lattman and Patrick J. Loll use clear examples and abundant illustrations to provide a concise and accessible primer on protein crystallography. Discussing the basics of diffraction, the behavior of two and threedimensional crystals, phase determination (including MIR and MAD phasing and molecular replacement), the Patterson function, and refinement, Lattman and Loll provide a complete overview of this important technique, illuminated by physical insights.The crisp writing style and simple illustrations will provide beginner crystallographers with a guide to the process of unraveling protein structure.

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Frequently Asked Questions

  • Q: What is the main focus of 'Protein Crystallography: A Concise Guide'? A: The book focuses on the techniques and principles of protein crystallography, explaining how X-ray diffraction is used to determine the three-dimensional structures of proteins.
  • Q: Who are the authors of this book? A: 'Protein Crystallography: A Concise Guide' is authored by Eaton E. Lattman and Patrick J. Loll, both of whom have extensive research and teaching experience in the field.
  • Q: What topics are covered in this guide? A: The book covers basics of diffraction, behavior of crystals, phase determination methods like MIR and MAD phasing, molecular replacement, and the Patterson function.
  • Q: Is this book suitable for beginners? A: Yes, the book is designed to be a concise and accessible primer for beginner crystallographers, with clear examples and illustrations.
  • Q: What is the format of the book? A: 'Protein Crystallography: A Concise Guide' is available in paperback format.
  • Q: How many pages does the book have? A: The book contains a total of 152 pages.
  • Q: When was this book published? A: The book was published on April 28, 2008.
  • Q: What is the condition of the book? A: The book is listed as 'New', ensuring it is in excellent condition for readers.
  • Q: What can I expect from the writing style of this book? A: The writing style is crisp and straightforward, making complex concepts easier to understand for readers.
  • Q: Is there any specific audience for this book? A: The book is primarily targeted towards students, researchers, and professionals interested in molecular biology and protein crystallography.