Regulationsmechanismen der Surestressantwort von Escherichia coli: Regulation auf transkriptionaler, posttranskriptionaler und p,Used

Regulationsmechanismen der Surestressantwort von Escherichia coli: Regulation auf transkriptionaler, posttranskriptionaler und p,Used

SKU: DADAX3838134591 In Stock
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Delivery time: 3-5 business days (USA)
Delivery time: 8-12 business days (International)
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Das berleben der Passage durch den Magen mit seinen extrem niedrigen pH Werten ist fr Enterobakterien, wie Escherichia coli oder Salmonella, essentiell zur Besiedelung des Darms bzw. fr die Virulenz pathogener Stmme. Dabei verfolgen sie vielfltige Strategien, deren Finesse seit einiger Zeit intensiv erforscht wird. Escherichia coli ist auerordentlich befhigt, in saurer Umgebung zu berleben, vergleichbar sogar mit Magenbewohnern wie Helicobacter pylori. Es bedient sich dabei des Glutamatabhngigen Sureresistenzsystemes, welches hochkomplex reguliert ist und so sehr dynamisch auf vernderte Umweltbedingungen reagieren kann. Wie in dieser Arbeit dargelegt wird, findet die Regulation dabei auf allen Ebenen statt: der Transkription ber eine Regulationskaskade, der Proteolyse durch Abbau des zentralen Regulators GadE und auch auf posttranskriptionaler Ebene. Es wird hier ein Modell des regulatorischen Netzwerkes entwickelt, das aufweist, wie Escherichia coli sehr elegant auf jede Situation die angemessene Antwort finden kann.

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Shipping & Returns

Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.

Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.

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Warranty

We provide a 2-year limited warranty, from the date of purchase for all our products.

If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.

This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).

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We accept payments with :
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