Title
Renal Transplantation: Sense and Sensitization (Developments in Nephrology, 21),Used
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In 1986, the Committee of Experts on Blood Transfusion and Immunohae tology of the Council of Europe chose for their Programme of Coordinated Research 'An investigation of the procurement and sharing of transplantable organs for potential recipients who are highly sensitized to HLAantigens'. This topic was of common concern to all centres practising renal transplan tion. The terms of reference of the study were: To estimate the number of patients who are virtually 'untransplantable' because of high sensitization in each European country. To study the nature of immunization in terms of the type and specificity of antibodies present in the blood and techniques used for their detection. To investigate possible practical solutions both current and future, invo ing crossmatching procedures, the circulation of reference material from patients, and the willingness of the national organizations to share resources. 4. To explore other methods of resolving this problem. Although the study did not offer the prospect of a brilliant new insight into the problem of high sensitization, it was unique in several ways: for the first time we saw all European organizations collaborating in a common project to provide information on their activities, their problems and the methods to resolve them; it introduced, for this subject, relatively novel statistical methods to investigate susceptibility to sensitization and factors affecting transplant outcome; it enabled a large database of transplanted highly sensitized patients and matched controls to be assembled, that would have been unavailable as a research resource at any single centre.
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- Q: What is the main focus of 'Renal Transplantation: Sense and Sensitization'? A: The book primarily focuses on the procurement and sharing of transplantable organs for patients who are highly sensitized to HLA-antigens, exploring the challenges and solutions in renal transplantation.
- Q: Who authored the book and what is their background? A: The book is authored by S.M. Gore, who brings expertise in nephrology and immunology, providing insights into the complexities of renal transplantation.
- Q: When was 'Renal Transplantation: Sense and Sensitization' published? A: The book was published on October 31, 1988.
- Q: What is the binding type of this book? A: The book is available in hardcover binding, which is known for its durability and quality.
- Q: How many pages does the book contain? A: The book contains a total of 334 pages.
- Q: Is this book suitable for beginners in the field of nephrology? A: While the book provides valuable insights, it may be more suitable for those with a basic understanding of nephrology, as it discusses advanced topics related to sensitization in renal transplantation.
- Q: What condition is the book in? A: The book is listed as 'New', indicating that it is in pristine condition and has not been previously used.
- Q: What category does this book fall under? A: This book falls under the category of Immunology.
- Q: Are there any specific features highlighted in the book? A: One of the key features of the book is that it is a 'Used Book in Good Condition', which suggests it may have been previously owned but remains intact and functional.
- Q: What type of information can I expect to find in this book? A: Readers can expect to find information on high sensitization to HLA-antigens, statistical methods for investigating transplant outcomes, and collaborative efforts among European organizations in the field of renal transplantation.