If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, withing 24 hours on weekdays.
Customer service
All questions about your order, return and delivery must be sent to our customer service team by e-mail at yourstore@yourdomain.com
Sale & Press
If you are interested in selling our products, need more information about our brand or wish to make a collaboration, please contact us at press@yourdomain.com
Help
If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, withing 24 hours on weekdays.
Customer service
All questions about your order, return and delivery must be sent to our customer service team by e-mail at yourstore@yourdomain.com
Sale & Press
If you are interested in selling our products, need more information about our brand or wish to make a collaboration, please contact us at press@yourdomain.com
Candida glabrata es una levadura haploide no dimrfica filogenticamente ms cercana a Saccharomyces cerevisiae que a Candida albicans. Parte del xito de C. glabrata para sobrevivir en el hospedero, puede deberse a la habilidad para evadir eficientemente las Especies Reactivas de Oxgeno (ERO) producidas por las clulas fagocticas. C. glabrata posee solo una catalasa (CTA1), la cual se induce dentro de los macrfagos del hospedero y le permite resistir a altas concentraciones de perxido de hidrgeno (H2O2), 1000 mM in vitro. En contraste, S. cerevisiae posee dos isoenzimas de catalasa, una peroxisomal (Cta1p) y otra citoslica (Ctt1p) que son reguladas diferencialmente, sin embargo, no es tan resistente a H2O2 como Candida glabrata. Estos datos sugieren que la respuesta al estrs oxidativo juega un papel importante para la sobrevivencia de este patgeno en el hospedero. Para determinar como se regula la catalasa de C. glabrata construimos dos fusiones con GFP: una traduccional PCgCTA1CTA1::GFP y otra transcripcional PCTA1::GFP. Complementamos mutantes de S. cerevisiae con CgCtaI y finalmente realizamos mutaciones puntuales en los motivos de importacin al peroxisoma.
⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer,
birth defects, or other reproductive harm.
For MAP (Minimum Advertised Price) violations and Intellectual Property (IP) or Trademark concerns, please contact:
support@ergodebooks.com
⚠️ California Proposition 65 Warning: Some products sold on this website may expose you to chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm. For more information, visit www.P65Warnings.ca.gov.
