Title
Resistencia a estrs oxidativo en Candida glabrata, un hongo patgeno: Regulacin de la Catalasa I (Spanish Edition),Used
Delivery time: 8-12 business days (International)
Candida glabrata es una levadura haploide no dimrfica filogenticamente ms cercana a Saccharomyces cerevisiae que a Candida albicans. Parte del xito de C. glabrata para sobrevivir en el hospedero, puede deberse a la habilidad para evadir eficientemente las Especies Reactivas de Oxgeno (ERO) producidas por las clulas fagocticas. C. glabrata posee solo una catalasa (CTA1), la cual se induce dentro de los macrfagos del hospedero y le permite resistir a altas concentraciones de perxido de hidrgeno (H2O2), 1000 mM in vitro. En contraste, S. cerevisiae posee dos isoenzimas de catalasa, una peroxisomal (Cta1p) y otra citoslica (Ctt1p) que son reguladas diferencialmente, sin embargo, no es tan resistente a H2O2 como Candida glabrata. Estos datos sugieren que la respuesta al estrs oxidativo juega un papel importante para la sobrevivencia de este patgeno en el hospedero. Para determinar como se regula la catalasa de C. glabrata construimos dos fusiones con GFP: una traduccional PCgCTA1CTA1::GFP y otra transcripcional PCTA1::GFP. Complementamos mutantes de S. cerevisiae con CgCtaI y finalmente realizamos mutaciones puntuales en los motivos de importacin al peroxisoma.
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For more information, please visit www.P65Warnings.ca.gov.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.