Title
Role of apoptosis in neuroinflammation: Apoptosis Inhibition Can Be Threatening in Ainduced Neuroinflammation, Through Promotin,Used
Delivery time: 8-12 business days (International)
Beta Amyloid peptide (A), specifically A (142) is toxic to neurons and is hence strongly associated with loss of brain function through the course of Alzheimers disease. This deposition induces neuronal death and apoptosis. Extensive studies in recent years have focused on Amediated microglia activation with regard to secretion of pro inflammatory cytokines such as TNFa. TNFa induces two distinct pathways: one of them is apoptosis and the other one is NF?B activation and eventually cell survival and proliferation.One of the questions that came to us was whether there is any relationship between these two path ways and blocking one pathway results in boosting the other one. To probe this issue, we blocked apoptosis and measure NF?B activation. Another question arose as the role of apoptosis in neuroinflammation. Whether apoptosis is a protective or destructive mechanism? To achieve this goal, we inhibited apoptosis and evaluated some intracellular changes such as: cMyc as a protooncogene, Hsp70 as a hallmark of cancer that is up regulated by stress and toxins and p53 as a tumor suppressor protein.
By changing our most important processes and
products, we have already made a big leap forward. This ranges from the
increased use of more sustainable fibers to the use of more
environmentally friendly printing processes to the development of
efficient waste management in our value chain.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.