Title
Role of Matrix metalloproteinase in Cancer development and progression: Significance of Matrix metalloproteinases (MMPs)in colon,Used
Delivery time: 8-12 business days (International)
Colon cancer is the third most common form of cancer and the second leading cause of death among cancer patients. Therapeutic agents that can down regulate the expression of the enzyme matrix metalloproteinases (MMPs) in colorectal tumors may prove effective in the treatment of colorectal tumor, given the fact that this is highly metastatic in nature. Nitric oxide (NO), a free radical, plays major role in many signaling pathways takes the lead role in colon cancer progression. Emodin, a naturally occurring anthraquinone suppresses the NO mediated up regulation of matrix metalloproteinases. The study reveals that emodin can be targeted as an effective anti metastatic agent in NO induced tumor progression. The methodology involved detecting the non cytotoxic concentration of exogenous nitric oxide releaser (SNP) and emodin in WiDr cell line. Molecular level analysis of matrix metalloproteinase mRNA levels in SNP and emodin treated cells shows a clear correlation of the involvement of these enzymes in WiDr cell migration and the inhibitory action of emodin on cell migration.
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⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.