Title
Sntesis de nuevos inhibidores del Pirofosfato de Farnesilo: Sntesis de nuevas Tioureas y Ureas (Spanish Edition),Used
Delivery time: 8-12 business days (International)
En esta Tesis iniciamos una lnea completamente nueva basada en la bsqueda de antimetabolitos del pirofosfato de farnesilo. ste es el sustrato de numerosos enzimas importantes en rutas biosintticas claves para el metabolismo de las celulas y de los organismos. As, es transformado por la escualeno sintetasa en escualeno, precursor de todos los esteroides. Inhibir la escualeno sintetasa podra ayudar a controlar el nivel de colesterol en los organismos superiores o podra interferir en el crecimiento bacteriano en el caso de las escualenos sintetasas procariotas. Por otra parte, el pirofosfato de farnesilo es sustrato de la farnesiltransferasa, responsable de la farnesilacin, y por tanto, activacin, de protenas, como la RAS, que juegan un papel clave en la transduccin de seales. Esta transduccin de seales est descontrolada en las clulas cancerosas. La inhibicin de la farnesilacin, al no activar a RAS, detiene el proceso de transduccin y lleva a la clula cancerosa a la muerte...
By changing our most important processes and
products, we have already made a big leap forward. This ranges from the
increased use of more sustainable fibers to the use of more
environmentally friendly printing processes to the development of
efficient waste management in our value chain.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.