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Stem Cells And Extracellular Matrices (Colloquium Series On Stem Cell Biology),Used
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Stem cells have great potential in regenerative medicine and tissue injury. Regulation of stem cell homeostasis in a 3D microenvironment is controlled by the niche components that influence stem cell fate, regulation, and function. It is therefore necessary to understand the mechanisms of cellcell interaction, molecular cross talk between stem cells and their extracellular matrix (ECM) environment. The adhesion molecules play a pivotal role in establishing the cellcell contact and subsequent integration with the ECM. This understanding is the basis for establishing design criteria for biomimetic. The integrated approach by biologists, material science engineers, biomedical engineers, and clinicians is the key in the development of tissue engineered constructs for effective translation to clinics.Table of Contents: Abbreviations / Introduction to Stem Cell Biology and Niche Components / ECMStructure and Organization / ECM Control, Regulation on Stem Cell Fate and Function / ECM and Stem Cell Cultures / Acknowledgments / Bibliography / Author Biography / Titles of Related Interest
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