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Help
If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, withing 24 hours on weekdays.
Customer service
All questions about your order, return and delivery must be sent to our customer service team by e-mail at yourstore@yourdomain.com
Sale & Press
If you are interested in selling our products, need more information about our brand or wish to make a collaboration, please contact us at press@yourdomain.com
Neisseria meningitidis genome contains 2158 protein coding regions. Nearly, half of the ORFs belongs to different functional classes. Sequence analysis of N. meningitidis hypothetical proteins using InterProScan and MPsrch resulted in the identification of 9 putative peptidases. Elegant bioinformatics studies provided functional information regarding the ORF NMB1147 to be an aspartate protease with a protein fold similar to CapA protein. Molecular cloning and expression of synthetic NMB1147 gene was carried out. The NMB1147 protein was expressed as inclusion bodies which were then solubilized followed by purification and refolding. Functional studies of HslVU proteasechaperone complex were also carried out for the identification of small molecules capable of activating HslV protease in the absence of its allosteric activator, HslU or HslU Ctail, using virtual screening of an inhouse WADB compound library. Structural bioinformatics studies of four N. meningitidis proteins were also carried out.
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⚠️ California Proposition 65 Warning: Some products sold on this website may expose you to chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm. For more information, visit www.P65Warnings.ca.gov.
