Title
Synthesis of New N,NDisubstituted Aryl and Alkylaryl Sulphonamides: And Their Antimicrobial Properties,Used
Delivery time: 8-12 business days (International)
The reaction of atoluenesulphonyl chloride with various readily available amino acids in basic medium afforded atoluenesulphonamides (1ak) which were amidated with diethyl amine to obtain new N,Ndiethylalkanamido sulphonamide derivatives (2ak). The electrophilic addition of ptoluenesulphonyl chloride with various amino acids' nitrogen gave ptolylsulphonamide derivatives (4ak) which upon further reaction with diethylamine afforded N,Ndiethylamido substituted sulphonamide moieties (5ak). Sulphonylation of the amino acids with benzenesulphonyl chloride yielded benzenesulphonamides (7ak) which were amidated to afford N,Ndiethylamido benzenesulphonamide derivatives, (8ak). The chemical structures were confirmed by elemental analysis and spectroscopic techniques which involved FTIR, Mass Spectra, 1H and 13CNMR. The antimicrobial properties of the synthesized sulphonamides (fifty five compounds) were determined on Staphylococcus aureus and Escherichia coli using agar diffusion method where (1a) was the most active compound against Staphylococcus aureus at MIC value of 1.8 g/mL while (2k) and (5j) were the most active on Escherichia coli at MIC of 12.5 g/mL.
By changing our most important processes and
products, we have already made a big leap forward. This ranges from the
increased use of more sustainable fibers to the use of more
environmentally friendly printing processes to the development of
efficient waste management in our value chain.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.
Secure Payment
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.