Title
Telomerase Activity in Normal and Neoplastic Lymph Nodes in the Dog: Telomerase, the Enzyme that Provides Neoplastic Cells of Im,Used
Delivery time: 8-12 business days (International)
One of the several differences between a normal and a neoplastic cell is that there is a physiological limit to the number of possible cell replications in the former, whereas it appears to be unlimited in the latter. For this reason, cancer cells are thought to undergo a phenomenon of immortalization. The chromosome extremities contain structurally defined elements called telomeres. In normal somatic cells, each mitotic cycle leads to a reduction of telomere length until a critical point is reached. Telomere erosion to this critical length presents a signal for the cell to arrest further divisions and to undergo cellular senescence or to activate apoptosis. Telomeres that avoid critical shortening could, theoretically, replicate endlessly, thereby immortalizing the cell. One mechanism to restore telomere length is the activation of a specific reverse transcriptase called telomerase. Upregulation of the telomerase enzyme provides immortalizing capacity to neoplastic cells.
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Shipping & Returns
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.