Title
The Art of Biochemical Synthesis: Chemical Synthesis of Proteins Containing Posttranslational Modifications and PNAtemplated D,Used
Delivery time: 8-12 business days (International)
As the most important molecules, proteins often undergo posttranslational modifications (PTM) to carry out their functions. In my study, two methods have been developed for the synthesis of proteins containing PTMs. The first method is chemical ligation at valine residue. The thioacid capture ligation was found to be more efficient to overcome steric hindrance of the tertiary thiol group in penicillamine compared with thioestermediated ligation. The second method is a direct and easytouse approach to introducing sitespecific acetylation onto recombinant proteins. The free thiol of cysteine was reacted with Nvinylacetamide (NVA) by radicalmediated thiolene coupling to generate acetyl4thialysine (sLys (Ac)) which is anacetyllysine analog. In the last part of this work, we have also introduced a new strategy for selective disulfide formation directed by PNA pairing. This method can be more useful than the DNAtemplated reaction systems.
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
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We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
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