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In all eukaryotic cells, each fundamental processcycle progression and its control, protein secretion and targeting, transcription and its regulation, mRNA processing, and DNA replicationaccomplished by essentially identical cellular machinery composed of essentially identical protein components. This conservation of function has catapulted the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe from parochial backwaters to the forefront of experimental molecular biology: What is true for a yeast is true for an elephant, and in experiments, you can get the answer a lot faster from a yeast. This burgeoning appreciation of yeasts as model systems for the study of fundamental cellular processes has highlighted the need for an update of the seminal 1981 monograph The Molecular Biology of the Yeast Saccharomyces. This need is now met by the publication of a threevolume series to serve as the authoritative sequel. The first volume focuses on the genome organization of the yeast Saccharomyces as well as protein translation and its regulation and energy metabolism. Subsequent volumes emphasize such topics as the cell cycle, secretion, and transcription.
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