Timo y nutricin. Estudio en modelo experimental: Efecto de la dieta sobre la actividad de Adenosina Deaminasa en timo (Spanish,Used

Timo y nutricin. Estudio en modelo experimental: Efecto de la dieta sobre la actividad de Adenosina Deaminasa en timo (Spanish,Used

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SKU: DADAX3659008532
Brand: Eae Editorial Academia Espanola
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Trabajos previos de nuestro grupo en modelo experimental en rata en crecimiento, han demostrado que desequilibrios nutricionales provocan alteracin en las etapas de diferenciacin y maduracin de los linfocitos T. Teniendo en cuenta la ntima relacin entre la actividad de Adenosina Deaminasa (ADA) , con el desarrollo y funcionamiento de los linfocitos T, el objetivo de este trabajo es estudiar en timo de rata en crecimiento activo, los efectos de: a) malnutricin proteica leve, moderada y severa al destete; b) subnutricin durante la lactancia ; c) administracin , al destete, de dietas con baja concentracin proteica y distorsin en su perfil de aminocidos indispensables y d) administracin de dieta de recuperacin, sobre los cuadros surgidos en a) y c), a travs de la actividad de dicha enzima. Los resultados demuestran que los diferentes desequilibrios nutricionales inducen disminucin del peso del timo e incremento en la actividad de ADA ; la administracin de la dieta de recuperacin fue capaz de revertir dichos efectos.

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