Title
Topical absorption and toxicity studies of hydrocarbons in skin: Methods and protocols for investigation of jet fuel induced der,Used
Delivery time: 8-12 business days (International)
Dermatitis is a major health concern associated with jet fuel exposures. The initial study addressed the possible mechanism for additive interactions on hydrocarbon disposition in synthetic and biological membranes. The remaining studies focused on neat hydrocarbon absorption and toxicity in pig skin. A dose related increase in percutaneous absorption of aromatic hydrocarbons was observed. This finding focuses attention to occupational settings where workers are repeatedly exposed to fuels. To assess the effects of jet fuel preexposure on subsequent hydrocarbon dermal absorption, pigs were exposed to JP8 soaked cotton with 4 repeated daily applications to mimic the occupational scenario. There was a 23 and 34 fold increase in absorption of short chain aliphatic and most of the aromatic hydrocarbons through 1 and 4day JP8 preexposed skin, respectively. Stratum corneum studies with FTIR spectroscopy suggested that lipid extraction might be the primary mechanism for this increase in hydrocarbon absorption. Finally, in vivo studies with the individual fuel hydrocarbons were conducted to identify the causative agents in fuel induced skin irritation.
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⚠️ WARNING (California Proposition 65):
This product may contain chemicals known to the State of California to cause cancer, birth defects, or other reproductive harm.
For more information, please visit www.P65Warnings.ca.gov.
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Shipping & Returns
Shipping
We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
Returns
To facilitate a smooth return process, a Return Authorization (RA) Number is required for all returns. Returns without a valid RA number will be declined and may incur additional fees. You can request an RA number within 15 days of the original delivery date. For more details, please refer to our Return & Refund Policy page.
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Warranty
We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.
We accept payments with :
Visa, MasterCard, American Express, Paypal, Shopify Payments, Shop Pay and more.