Toward A History Of Epistemic Things: Synthesizing Proteins In The Test Tube (Writing Science),Used

Toward A History Of Epistemic Things: Synthesizing Proteins In The Test Tube (Writing Science),Used

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SKU: SONG0804727864
Brand: Stanford University Press
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In this powerful work of conceptual and analytical originality, the author argues for the primacy of the material arrangements of the laboratory in the dynamics of modern molecular biology. In a postKuhnian move away from the hegemony of theory, he develops a new epistemology of experimentation in which research is treated as a process for producing epistemic things.A central concern of the book is the basic question of how novelty is generated in the empirical sciences. In addressing this question, the author brings French poststructuralist thinkingnotably Jacques Derridas concepts of diffrance and historialityto bear on the construction of epistemic things. Historiographical perspective shifts from the actors minds to their objects of manipulation.These epistemological and historical issues are illuminated in a detailed case study of a particular laboratory, that of the oncologist and biochemist Paul C. Zamecnik and his colleagues, located in a specific settingthe Collis P. Huntington Memorial Hospital of Harvard University at the Massachusetts General Hospital of Boston. The author traces how, between 1945 and 1965, this group developed an experimental system for synthesizing proteins in the test tube that put Zamecniks research team at the forefront of those who led biochemistry into the era of molecular biology.

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For more information, please visit www.P65Warnings.ca.gov.

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