Title
Translational GTPases: Structural, biochemical and thermodynamical aspects,New
Delivery time: 8-12 business days (International)
Protein biosynthesis is a core process in all livingorganisms. Assembly of the protein chain fromaminoacids is catalysed by the ribosome, an ancientand extremely complex macromolecular machine. Severaldifferent classes of accessory molecules are involvedin translation, and one set of them, calledtranslational GTPases (trGTPases) is the focus ofthis work. These proteins oscillate between theirGTP and GDPbound states via regulated cycles of GTPhydrolysis and exchange of GDP for GTP. The exchangeof GDP for GTP is accelerated by the GDP/GTP ExchangeFactor (GEF), while hydrolase activity of the GTPaseis stimulated by the GTPaseActivating Protein (GAP).The conformation of the GTPase in complex with GTPusually differs from that in complex with GDP, andthese structural changes serve as a signal for apartner molecule, inducing changes in its conformation. This book provides a comprehensive overview of thestate of the art in trGTPase research, touching uponstructural, biochemical and thermodynamical aspectsand would be a useful reference for anybodyinterested in the mechanisms and regulation ofprotein biosynthesis.
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We ship your order within 2–3 business days for USA deliveries and 5–8 business days for international shipments. Once your package has been dispatched from our warehouse, you'll receive an email confirmation with a tracking number, allowing you to track the status of your delivery.
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We provide a 2-year limited warranty, from the date of purchase for all our products.
If you believe you have received a defective product, or are experiencing any problems with your product, please contact us.
This warranty strictly does not cover damages that arose from negligence, misuse, wear and tear, or not in accordance with product instructions (dropping the product, etc.).
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